This guide covers 2 new american restaurant options in St. Louis. Guests rate them 4.6 out of 5 on average. Most of them are spread across Downtown West, The Hill, so those are the areas to start with.

All New American restaurant in St. Louis

Blood & Sand

4.4 562 reviews

Blood & Sand is a fine dining restaurant in downtown St. Louis, offering hand-crafted cocktails and inventive New American cuisine. It is a nationally recognized establishment, known for its exceptional service and extraordinary dining experience, which has earned it the Wine Spectator Award of Excellence year after year. The restaurant is open to the public, with no membership required, and welcomes everyone, regardless of whether it's their first visit or their fiftieth. Blood & Sand offers a range of menus, including a 5-course tasting menu, a 10-course tasting menu, and an à la carte dinner menu, as well as a bar cuisine menu and a drink menu featuring cocktails and wines by the glass. The restaurant also offers a tailored chef's tasting experience and private dining and large party options. For those who dine with them often, the membership program adds extra perks, including discounted pricing, complimentary champagne, and half-portion tater tots. The restaurant is located at 1500 St. Charles Street in downtown St. Louis, and reservations are encouraged and required on Friday and Saturday evenings. The hours of operation are Monday through Thursday from 5 to 11 PM, and Friday and Saturday from 5 to 12 PM. The phone number is 314 241 SAND (7263), and the email address is [email protected].

Opening hours
  • Monday5–11 PM
  • Tuesday5–11 PM
  • Wednesday5–11 PM
  • Thursday5–11 PM
  • Friday5 PM–12 AM
  • Saturday5 PM–12 AM
  • SundayClosed

Anthonino’s Taverna

4.7 4,248 reviews

Anthonino's Taverna is a family-owned restaurant serving Italian and Greek cuisine. Established in 2003, it is a St. Louis tradition, offering a unique mix of traditional Italian dishes and Greek specialties. The restaurant is located on The Hill in St. Louis, a neighborhood known for its Italian-American culture. Anthonino's Taverna is known for its award-winning dishes, including its famous toasted ravioli, which has been featured on Food Network. The restaurant has received numerous awards and accolades, including being voted "Best Italian Restaurant" in RFT's "The best of St. Louis" in 2011. The menu features a variety of pasta dishes, pizzas, and entrees, including Greek specialties such as dolmathes and Greek yogurt tzatziki. The restaurant's atmosphere is cozy and relaxed, with a mix of old-world charm and modern style. The kitchen prepares most dishes from scratch, using fresh, locally-sourced ingredients whenever possible. The restaurant has a private banquet space and catering menu available for events and parties, making it a popular choice for both intimate gatherings and large celebrations.

Opening hours
  • Monday11 AM–10 PM
  • Tuesday11 AM–10 PM
  • Wednesday11 AM–10 PM
  • Thursday11 AM–10 PM
  • Friday11 AM–10 PM
  • Saturday11 AM–10 PM
  • SundayClosed